Diffusion imaging of nigral alterations in early Parkinson's disease with dopaminergic deficits.
Identifieur interne : 000268 ( Main/Exploration ); précédent : 000267; suivant : 000269Diffusion imaging of nigral alterations in early Parkinson's disease with dopaminergic deficits.
Auteurs : Norbert Schuff [États-Unis] ; I-Wei Wu [États-Unis] ; Shannon Buckley [États-Unis] ; Eric D. Foster [États-Unis] ; Christopher S. Coffey [États-Unis] ; Darren R. Gitelman [États-Unis] ; Susan Mendick [États-Unis] ; John Seibyl [États-Unis] ; Tanya Simuni [États-Unis] ; Yu Zhang [États-Unis] ; Joseph Jankovic [États-Unis] ; Christine Hunter [États-Unis] ; Caroline M. Tanner [États-Unis] ; Linda Rees [États-Unis] ; Stewart Factor [États-Unis] ; Daniela Berg [Allemagne] ; Isabel Wurster [Allemagne] ; Katharina Gauss [Allemagne] ; Fabienne Sprenger [Autriche] ; Klaus Seppi [Autriche] ; Werner Poewe [Autriche] ; Brit Mollenhauer [Allemagne] ; Susanne Knake [Allemagne] ; Zoltan Mari [États-Unis] ; Arita Mccoy [États-Unis] ; Madelaine Ranola [Australie] ; Kenneth Marek [États-Unis]Source :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2015.
Abstract
This study reports the baseline characteristics of diffusion tensor imaging data in Parkinson's disease (PD) patients and healthy control subjects from the Parkinson's Progression Markers Initiative. The main goals were to replicate previous findings of abnormal diffusion imaging values from the substantia nigra. in a large multicenter cohort and determine whether nigral diffusion alterations are associated with dopamine deficits.
DOI: 10.1002/mds.26325
PubMed: 26260437
Affiliations:
- Allemagne, Australie, Autriche, États-Unis
- Bade-Wurtemberg, Californie, Connecticut, District de Kassel, District de Tübingen, Géorgie (États-Unis), Hesse (Land), Illinois, Iowa, Maryland, Texas, Tyrol (Land)
- Cassel (Hesse), Houston, Innsbruck, Iowa City, Sydney, Tübingen
- Baylor College of Medicine, Université de l'Iowa, Université de médecine d'Innsbruck
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type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Wu, I Wei" sort="Wu, I Wei" uniqKey="Wu I" first="I-Wei" last="Wu">I-Wei Wu</name><affiliation wicri:level="2"><nlm:affiliation>Department of Veteran Affairs Medical Center, San Francisco, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veteran Affairs Medical Center, San Francisco, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Buckley, Shannon" sort="Buckley, Shannon" uniqKey="Buckley S" first="Shannon" last="Buckley">Shannon Buckley</name><affiliation wicri:level="2"><nlm:affiliation>Department of Veteran Affairs Medical Center, San Francisco, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veteran Affairs Medical Center, San Francisco, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Foster, Eric D" sort="Foster, Eric D" uniqKey="Foster E" first="Eric D" last="Foster">Eric D. Foster</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, Iowa, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, Iowa</wicri:regionArea><placeName><region type="state">Iowa</region><settlement type="city">Iowa City</settlement></placeName><orgName type="university">Université de l'Iowa</orgName></affiliation></author><author><name sortKey="Coffey, Christopher S" sort="Coffey, Christopher S" uniqKey="Coffey C" first="Christopher S" last="Coffey">Christopher S. Coffey</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, Iowa, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, Iowa</wicri:regionArea><placeName><region type="state">Iowa</region><settlement type="city">Iowa City</settlement></placeName><orgName type="university">Université de l'Iowa</orgName></affiliation></author><author><name sortKey="Gitelman, Darren R" sort="Gitelman, Darren R" uniqKey="Gitelman D" first="Darren R" last="Gitelman">Darren R. Gitelman</name><affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Mendick, Susan" sort="Mendick, Susan" uniqKey="Mendick S" first="Susan" last="Mendick">Susan Mendick</name><affiliation wicri:level="2"><nlm:affiliation>Institute for Neurodegenerative Disorders (IND) and Molecular Neuroimaging, LLC (MNI), New Haven, Connecticut, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Neurodegenerative Disorders (IND) and Molecular Neuroimaging, LLC (MNI), New Haven, Connecticut</wicri:regionArea><placeName><region type="state">Connecticut</region></placeName></affiliation></author><author><name sortKey="Seibyl, John" sort="Seibyl, John" uniqKey="Seibyl J" first="John" last="Seibyl">John Seibyl</name><affiliation wicri:level="2"><nlm:affiliation>Institute for Neurodegenerative Disorders (IND) and Molecular Neuroimaging, LLC (MNI), New Haven, Connecticut, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Neurodegenerative Disorders (IND) and Molecular Neuroimaging, LLC (MNI), New Haven, Connecticut</wicri:regionArea><placeName><region type="state">Connecticut</region></placeName></affiliation></author><author><name sortKey="Simuni, Tanya" sort="Simuni, Tanya" uniqKey="Simuni T" first="Tanya" last="Simuni">Tanya Simuni</name><affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Zhang, Yu" sort="Zhang, Yu" uniqKey="Zhang Y" first="Yu" last="Zhang">Yu Zhang</name><affiliation wicri:level="2"><nlm:affiliation>Department of Veteran Affairs Medical Center, San Francisco, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veteran Affairs Medical Center, San Francisco, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name><affiliation wicri:level="2"><nlm:affiliation>Baylor College of Medicine, Houston, Texas, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Baylor College of Medicine, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName><orgName type="university" n="3">Baylor College of Medicine</orgName></affiliation></author><author><name sortKey="Hunter, Christine" sort="Hunter, Christine" uniqKey="Hunter C" first="Christine" last="Hunter">Christine Hunter</name><affiliation wicri:level="2"><nlm:affiliation>Baylor College of Medicine, Houston, Texas, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Baylor College of Medicine, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Tanner, Caroline M" sort="Tanner, Caroline M" uniqKey="Tanner C" first="Caroline M" last="Tanner">Caroline M. Tanner</name><affiliation wicri:level="2"><nlm:affiliation>Department of Veteran Affairs Medical Center, San Francisco, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veteran Affairs Medical Center, San Francisco, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Rees, Linda" sort="Rees, Linda" uniqKey="Rees L" first="Linda" last="Rees">Linda Rees</name><affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, University of California, San Francisco, CA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, University of California, San Francisco, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Factor, Stewart" sort="Factor, Stewart" uniqKey="Factor S" first="Stewart" last="Factor">Stewart Factor</name><affiliation wicri:level="2"><nlm:affiliation>Emory University, Atlanta, Georgia, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Emory University, Atlanta, Georgia</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Berg, Daniela" sort="Berg, Daniela" uniqKey="Berg D" first="Daniela" last="Berg">Daniela Berg</name><affiliation wicri:level="3"><nlm:affiliation>University of Tuebingen, Tuebingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Tuebingen, Tuebingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Wurster, Isabel" sort="Wurster, Isabel" uniqKey="Wurster I" first="Isabel" last="Wurster">Isabel Wurster</name><affiliation wicri:level="3"><nlm:affiliation>University of Tuebingen, Tuebingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Tuebingen, Tuebingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Gauss, Katharina" sort="Gauss, Katharina" uniqKey="Gauss K" first="Katharina" last="Gauss">Katharina Gauss</name><affiliation wicri:level="3"><nlm:affiliation>University of Tuebingen, Tuebingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Tuebingen, Tuebingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Sprenger, Fabienne" sort="Sprenger, Fabienne" uniqKey="Sprenger F" first="Fabienne" last="Sprenger">Fabienne Sprenger</name><affiliation wicri:level="1"><nlm:affiliation>Innsbruck Medical University, Innsbruck, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Innsbruck Medical University, Innsbruck</wicri:regionArea><wicri:noRegion>Innsbruck</wicri:noRegion></affiliation></author><author><name sortKey="Seppi, Klaus" sort="Seppi, Klaus" uniqKey="Seppi K" first="Klaus" last="Seppi">Klaus Seppi</name><affiliation wicri:level="1"><nlm:affiliation>Innsbruck Medical University, Innsbruck, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Innsbruck Medical University, Innsbruck</wicri:regionArea><wicri:noRegion>Innsbruck</wicri:noRegion></affiliation></author><author><name sortKey="Poewe, Werner" sort="Poewe, Werner" uniqKey="Poewe W" first="Werner" last="Poewe">Werner Poewe</name><affiliation wicri:level="1"><nlm:affiliation>Innsbruck Medical University, Innsbruck, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Innsbruck Medical University, Innsbruck</wicri:regionArea><wicri:noRegion>Innsbruck</wicri:noRegion><placeName><settlement type="city">Innsbruck</settlement><region nuts="2" type="region">Tyrol (Land)</region></placeName><orgName type="university">Université de médecine d'Innsbruck</orgName></affiliation></author><author><name sortKey="Mollenhauer, Brit" sort="Mollenhauer, Brit" uniqKey="Mollenhauer B" first="Brit" last="Mollenhauer">Brit Mollenhauer</name><affiliation wicri:level="3"><nlm:affiliation>Paracelsus-Elena Klinik, Kassel, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Paracelsus-Elena Klinik, Kassel</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Kassel</region><settlement type="city">Cassel (Hesse)</settlement></placeName></affiliation></author><author><name sortKey="Knake, Susanne" sort="Knake, Susanne" uniqKey="Knake S" first="Susanne" last="Knake">Susanne Knake</name><affiliation wicri:level="3"><nlm:affiliation>Paracelsus-Elena Klinik, Kassel, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Paracelsus-Elena Klinik, Kassel</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Kassel</region><settlement type="city">Cassel (Hesse)</settlement></placeName></affiliation></author><author><name sortKey="Mari, Zoltan" sort="Mari, Zoltan" uniqKey="Mari Z" first="Zoltan" last="Mari">Zoltan Mari</name><affiliation wicri:level="2"><nlm:affiliation>Johns Hopkins University, Baltimore, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Johns Hopkins University, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Mccoy, Arita" sort="Mccoy, Arita" uniqKey="Mccoy A" first="Arita" last="Mccoy">Arita Mccoy</name><affiliation wicri:level="2"><nlm:affiliation>Johns Hopkins University, Baltimore, Maryland, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Johns Hopkins University, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Ranola, Madelaine" sort="Ranola, Madelaine" uniqKey="Ranola M" first="Madelaine" last="Ranola">Madelaine Ranola</name><affiliation wicri:level="3"><nlm:affiliation>Macquarie University, Sydney, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Macquarie University, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement></placeName></affiliation></author><author><name sortKey="Marek, Kenneth" sort="Marek, Kenneth" uniqKey="Marek K" first="Kenneth" last="Marek">Kenneth Marek</name><affiliation wicri:level="2"><nlm:affiliation>Institute for Neurodegenerative Disorders (IND) and Molecular Neuroimaging, LLC (MNI), New Haven, Connecticut, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Neurodegenerative Disorders (IND) and Molecular Neuroimaging, LLC (MNI), New Haven, Connecticut</wicri:regionArea><placeName><region type="state">Connecticut</region></placeName></affiliation></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">This study reports the baseline characteristics of diffusion tensor imaging data in Parkinson's disease (PD) patients and healthy control subjects from the Parkinson's Progression Markers Initiative. The main goals were to replicate previous findings of abnormal diffusion imaging values from the substantia nigra. in a large multicenter cohort and determine whether nigral diffusion alterations are associated with dopamine deficits.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Autriche</li><li>États-Unis</li></country><region><li>Bade-Wurtemberg</li><li>Californie</li><li>Connecticut</li><li>District de Kassel</li><li>District de Tübingen</li><li>Géorgie (États-Unis)</li><li>Hesse (Land)</li><li>Illinois</li><li>Iowa</li><li>Maryland</li><li>Texas</li><li>Tyrol (Land)</li></region><settlement><li>Cassel (Hesse)</li><li>Houston</li><li>Innsbruck</li><li>Iowa City</li><li>Sydney</li><li>Tübingen</li></settlement><orgName><li>Baylor College of Medicine</li><li>Université de l'Iowa</li><li>Université de médecine d'Innsbruck</li></orgName></list><tree><country name="États-Unis"><region name="Californie"><name sortKey="Schuff, Norbert" sort="Schuff, Norbert" uniqKey="Schuff N" first="Norbert" last="Schuff">Norbert Schuff</name></region><name sortKey="Buckley, Shannon" sort="Buckley, Shannon" uniqKey="Buckley S" first="Shannon" last="Buckley">Shannon Buckley</name><name sortKey="Coffey, Christopher S" sort="Coffey, Christopher S" uniqKey="Coffey C" first="Christopher S" last="Coffey">Christopher S. Coffey</name><name sortKey="Factor, Stewart" sort="Factor, Stewart" uniqKey="Factor S" first="Stewart" last="Factor">Stewart Factor</name><name sortKey="Foster, Eric D" sort="Foster, Eric D" uniqKey="Foster E" first="Eric D" last="Foster">Eric D. Foster</name><name sortKey="Gitelman, Darren R" sort="Gitelman, Darren R" uniqKey="Gitelman D" first="Darren R" last="Gitelman">Darren R. Gitelman</name><name sortKey="Hunter, Christine" sort="Hunter, Christine" uniqKey="Hunter C" first="Christine" last="Hunter">Christine Hunter</name><name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name><name sortKey="Marek, Kenneth" sort="Marek, Kenneth" uniqKey="Marek K" first="Kenneth" last="Marek">Kenneth Marek</name><name sortKey="Mari, Zoltan" sort="Mari, Zoltan" uniqKey="Mari Z" first="Zoltan" last="Mari">Zoltan Mari</name><name sortKey="Mccoy, Arita" sort="Mccoy, Arita" uniqKey="Mccoy A" first="Arita" last="Mccoy">Arita Mccoy</name><name sortKey="Mendick, Susan" sort="Mendick, Susan" uniqKey="Mendick S" first="Susan" last="Mendick">Susan Mendick</name><name sortKey="Rees, Linda" sort="Rees, Linda" uniqKey="Rees L" first="Linda" last="Rees">Linda Rees</name><name sortKey="Seibyl, John" sort="Seibyl, John" uniqKey="Seibyl J" first="John" last="Seibyl">John Seibyl</name><name sortKey="Simuni, Tanya" sort="Simuni, Tanya" uniqKey="Simuni T" first="Tanya" last="Simuni">Tanya Simuni</name><name sortKey="Tanner, Caroline M" sort="Tanner, Caroline M" uniqKey="Tanner C" first="Caroline M" last="Tanner">Caroline M. Tanner</name><name sortKey="Wu, I Wei" sort="Wu, I Wei" uniqKey="Wu I" first="I-Wei" last="Wu">I-Wei Wu</name><name sortKey="Zhang, Yu" sort="Zhang, Yu" uniqKey="Zhang Y" first="Yu" last="Zhang">Yu Zhang</name></country><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Berg, Daniela" sort="Berg, Daniela" uniqKey="Berg D" first="Daniela" last="Berg">Daniela Berg</name></region><name sortKey="Gauss, Katharina" sort="Gauss, Katharina" uniqKey="Gauss K" first="Katharina" last="Gauss">Katharina Gauss</name><name sortKey="Knake, Susanne" sort="Knake, Susanne" uniqKey="Knake S" first="Susanne" last="Knake">Susanne Knake</name><name sortKey="Mollenhauer, Brit" sort="Mollenhauer, Brit" uniqKey="Mollenhauer B" first="Brit" last="Mollenhauer">Brit Mollenhauer</name><name sortKey="Wurster, Isabel" sort="Wurster, Isabel" uniqKey="Wurster I" first="Isabel" last="Wurster">Isabel Wurster</name></country><country name="Autriche"><noRegion><name sortKey="Sprenger, Fabienne" sort="Sprenger, Fabienne" uniqKey="Sprenger F" first="Fabienne" last="Sprenger">Fabienne Sprenger</name></noRegion><name sortKey="Poewe, Werner" sort="Poewe, Werner" uniqKey="Poewe W" first="Werner" last="Poewe">Werner Poewe</name><name sortKey="Seppi, Klaus" sort="Seppi, Klaus" uniqKey="Seppi K" first="Klaus" last="Seppi">Klaus Seppi</name></country><country name="Australie"><noRegion><name sortKey="Ranola, Madelaine" sort="Ranola, Madelaine" uniqKey="Ranola M" first="Madelaine" last="Ranola">Madelaine Ranola</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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